Saturday, August 22, 2009

Adrenergic Nerves - Sympathetic

i've got no life so yeah, revising pharmaco...a quick summary on adrenergic nerves...so, read if you want to... =)

Release> Response> Removal


>>>>Release - caused by AMPHETAMINE which acts as indirect adrenergic agonist Function of amphetamine: displaces NA from storage vesicles of adrenergic nerves/ causes more release of more NA (precursor of adrenaline) - amphetamine is a sympathomimetics which means mimics sympathetic effects


>>>Response - alpha (blood vessels) and beta (heart, lungs) -fight or flight response - increase heart rate, bronchodilation , vasoconstriction of skin, vasodilation of muscles, inhibit GIT(both alpha and beta)


>>>Removal- uptake 1 (recaptures) and 2 (taken in by tissues)
Uptake 1 blocked by COCAINE, seratonin, dopamine and NA ( dopamine and NA are precursors of adrenaline)

No comments:

Post a Comment